Michael Zavrel
Bioprocess Engineering
The focus of the professorship is the development of sustainable bioprocesses involving biocatalysts like enzymes and microorganisms. Biogenic raw materials are used which do not compete with the food chain such as agricultural residues and waste streams. The products are e.g. bio-based platform chemicals, biofuels, and biodegradable biopolymers. The professorship comprises enzymatic reactions, fermentation processes, downstream processing and bioprocess design. Specific research focus is laid on model-based process design, enzyme immobilization, tolerant fermentation processes, soft sensors, innovative downstream processing, and upscaling of bioprocesses. The professorship Bioprocess Engineering is located at the TUM Campus Straubing for Biotechnology and Sustainability.
Key publications:
Generalizability of Soft Sensors for Bioprocesses through Similarity Analysis and Phase-Dependent Recalibration, M. Siegl, M. Kämpf, D. Geier, B. Andreeßen, S. Max, M. Zavrel, T. Becker,* Sensors 2023, 23(4), 2178.
Systematic Determination of Intrinsic Reaction Parameters in Enzyme Immobilizates, M. Zavrel,* C. Michalik, T. Schwendt, T. Schmidt, M. B. Ansorge-Schumacher, C. Janzen, W. Marquardt, J. Büchs, A. C. Spiess,* Chem. Eng. Sci. 2009, 65(8), 2491–2499.
Mechanistic Kinetic Model for Symmetric Carboligations Using Benzaldehyde Lyase, M. Zavrel, T. Schmidt, C. Michalik, M. Ansorge-Schumacher, W. Marquardt, J. Büchs, A. C. Spiess, Biotechnol. Bioeng. 2008, 101(1), 27–38.
Press releases: